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I work as an international journalist and I travel a lot to countries with exotic nature. Every time when I am about to direct my steps to regions with malaria I take a course of Chloroquine. It helps me keep away from the disease and come back healthy. These medications can not be taken on a regular basis because of being very strong. So don't forget to consult with your doctor if you plan a trip to contaminated area. Malaria is a horrible disease and if you can prevent it don't hesitate. People talk about awful side effects after taking medications from malaria, but what I think is that vomiting and sweating is better than death anyway. The only side effect I experienced after starting on Chloroquine was mild fatigue. It soon disappeared though. So, think twice and then act!

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Chloroquine is unsuitable for sufferers from various complaints such as epilepsy and psoriasis but daily proguanil (brand name Paludrine) can be used in its place.

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Molecular Methods Molecular characterization: For some drugs (Chloroquine, SP and similar drugs, atovaquone), molecular markers have been identified that confer resistance.

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In most instances a mutation will be fatal for the parasite or the drug pressure will remove parasites that remain susceptible, however some resistant parasites will survive.

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Consult your doctor if you experience rash with eosinophilia and systemic symptoms (DRESS) syndrome after taking chloroquine.

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Chloroquine analogues are effective in the treatment of dermatomyositis (childhood or juvenile form).

There has been evidence to suggest that certain parasite-vector combinations can alternatively enhance or inhibit the transmission of resistant parasites, causing 'pocket-like' areas of resistance.

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SPS should be discontinued in patients who become constipated, and repeat doses should not be given to patients who have not passed a bowel movement.

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Known as artemisinin, it is today a very potent and effective antimalarial drug, especially in combination with other medicines (CDC, 2004a).

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